Protein Purification Reagents and Kits
AdipoGen ANGPTL3 FLD h rec
Recombinant Protein. Fibrinogen-like domain of human ANGPTL3 aa 224-460 is fused at the N-terminus to a FLAG -tag. Source/Host HEK 293 cells. Endotoxin <0.01EU/µg purified protein LAL test. Lyophilized. Contains PBS. ANGPTL3 Angiopoietin-like protein 3 regulates angiogenesis and also directly regulates lipid, glucose and energy metabolism. Angiopoietin-like 3 ANGPTL3 is a regulator of plasma triglyceride TRG levels due to its inhibitory action on the activity of lipoprotein lipase LPL. ANGPTL3 induces angiogenesis by binding to integrin alphavbeta3. ANGPTL3 is predominantly produced in the liver and can therefore be classified as a hepatokine. In the human plasma, ANGPTL3 is cleaved to released two fragments a N-terminal coiled-coil domain-containing fragment aa17-207 important for inhibiting the lipolysis of triglyceride and the C-terminal fibrinogen-like domain-containing fragment aa208-460.
AdipoGen ANGPTL8 msFc hrec
Protein. Mouse ANGPTL8 Betatrophin 22-198 is fused at the C-terminus to the Fc portion of human IgG1. Source HEK 293 cells. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized. Contains PBS 0.02% CHAPS. Purity >90% SDS-PAGE. ANGPTL8 Angiopoietin-like protein 8 RIFL Lipasin Betatrophin is a newly discovered secreted protein of 198 aa that was proposed to promote beta cell proliferation and improve glucose tolerance in mice. ANGPTL8 may also function in inhibition of lipase activity and on serum triglyceride regulation. ANGPTL8 is expressed in the liver and in white and brown adipose tissue of mice. In humans, ANGPTL8 is found to be predominantly expressed in the liver. ANGPTL8 levels are reduced by fasting and are elevated upon insulin resistance and during pregnancy. ANGPTL8, according to preliminary data could bind to the macrophage receptor Marco and also to RTN4R, a neuronal receptor.
AdipoGen IL-37 aa 46-218hrecHis
Protein. Human IL-37 aa Val46-Asp218 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <0.1EU/µg purified protein LAL test Lonza. Lyophilized from 0.2µm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity >95% SDS-PAGE. IL-37 IL-1F7 IL-1H4 is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells PBMCs and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor IL-18R and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide LPS-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
Cayman Chemical Cel-Based asy GlutathIon 3mg
An IRE1a inhibitor (IC50s 0.2 and 0.02 UM for RNase and kinase activity respectively) selective for IRE1a over Ron and FGFR1 (IC50s 4.4 and 17 UM) as well as a panel of 282 kinases at 10 UM inhibits ER stress-induced increases in the splicing of mRNA encoding XBP1 in eight multiple myeloma cell lines at 8 UM reduces viral replication in tick-borne encephalitis virus-infected SH-SY5Y and SNB-19 cells at 0.5 UM and tick-borne encephalitis virus-infected Caco-2 cells at 1 UM
American Research Products Inc GLUTATHIONE PEROXIDASE KIT BA0
5000265557 GLUTATHIONE PEROXIDASE KIT BA0
American Research Products Inc GLUTATHIONE S TRANSFERASE GST
5000265598 GLUTATHIONE S TRANSFERASE GST
BIOHIPPO Anti-Human BRAF/B-Raf (V600E) Antibody (SAA2068), 100 µg
BRAF/B-Raf (SAA2068) Recombinant Antibody (clone V600E) is a recombinant Mouse IgG2a, kappa antibody specific for BRAF/B-Raf (SAA2068). It reacts with Human. Suitable for ELISA. Recombinant production ensures high specificity and lot-to-lot reproducibility. Supplied as 100 ug.
Cayman Chemical 4-hydroxy Nonenal Glutathione
An internal standard for the quantification of 4-HNE-GSH by GC- or LC-MS
American Research Products Inc Human Glutathione S transferas
Human Glutathione S-transferase omega-1 (GSTO1) ELISA kit from CUSABIO Detection Range 31 2 pg/mL-2000 pg/mL Sensitivity 7 8 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Cayman Chemical S-NItroso-L-glutathIon 50mg
S-Nitroso-L-glutathione is an S-nitrosothiol NO donor based on naturally-occurring glutathione. It is a potent smooth muscle relaxant and inhibitor of platelet aggregation. Its stability in solution varies from seconds to hours depending on temperature, buffer composition, and metal content.{1277,5064,4274,3632}
ABclonal Technology Phospho-B-Raf-S445 Rabbit pAb
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome.